The Olive Oil Polyphenol Difference—Trephenol™
Our unique olive fruit extract Trephenol™ is a patented blend of key olive polyphenols derived from olives using an all-natural process. This patented ingredient has high concentrations of both hydroxytyrosol and tyrosol—2 extensively studied polyphenols in olive oil.1
- 100% natural
- Chemical- and pesticide-free
- Extracted from high-quality Spanish olives that are non-GMO (non-genetically modified organisms)
- Made using patented clean technology and recovered with water
Two softgels of PureVida™, taken daily for a week, provide the equivalent amount of olive polyphenols (hydroxytyrosol and tyrosol) as 2.5 liters of olive oil without the added calories and unwanted fats.
Curcumin C3 Complex®
Occurring naturally in turmeric roots, curcumin has long been believed to have powerful antioxidant and anti-inflammatory effects.2 Curcumin C3 Complex® (a registered trademark of Sabinsa Corporation) is a patented and clinically tested blend of curcumin, demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC)—collectively known as “curcuminoids”—developed and supplied by Sabinsa.3 Taken for a week, PureVida™ delivers 840 mg of curcumin.
Marine omega-3s, primarily the essential fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are anti-inflammatory polyunsaturated fatty acids (PUFAs) that are considered to be important for many of the body’s functions.4-9 The Joint Food and Agriculture Organization of the United Nations (FAO) along with World Health Organization (WHO) recommend daily doses of 250 mg/day of both EPA and DHA as part of a healthy diet.†,10,11 This may come in the form of 2 daily fish meals each week, as recommended by the American Heart Association (AHA).†,12,13 Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease.4-9 Two softgels of PureVida™ deliver 450 mg of EPA and 300 mg of DHA. When taken for a week, this is equivalent on average to more than 3 fish meals.
†The daily amount of EPA and DHA recommended varies depending on a person’s health status. Recommendations also vary depending on the recommending organizations and the evidence they evaluate. Many organizations recommend 250 mg/day of EPA/DHA to maintain overall good health and prevent deficiency. Similarly, the recommended amount of seafood or fatty fish consumption also varies, but generally is 2 servings of fatty fish/week or 8 oz of a variety of seafood. This provides the recommended 250 mg/day of EPA/DHA.11-14
aIn a prospective, multicenter, pilot study of 45 postmenopausal women (mean age 59 years) with Stage 0-IIIA hormone receptor−positive breast cancer receiving stable doses of adjuvant aromatase inhibitor therapy for 2 to 5 years from their diagnosis, PureVida™ significantly reduced C-reactive protein (CRP) levels (p<0.05). In 45 patients examined for safety, reported to "adverse events (AEs) included abdominal pain in 1 patient (2.2%), constipation in 5 patients (11.1%), headache in 3 patients (6.7%), and abnormal product taste (fish taste) in 14 patients (31.1%). No patients had to discontinue therapy due to AEs. This study was conducted by OliVentures. There has been substantial separate research into the potential benefits of each of the ingredients in PureVida™. The PureVida™ trial has not been peer reviewed and more research is needed before drawing any final conclusions.
*This product is not intended to diagnose, treat, cure, or prevent any disease. Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease. Limited clinical evidence indicates that PureVida™ may lower elevated CRP levels. CRP is one of several markers of inflammation in the body. Limited clinical evidence indicates that PureVida™ may reduce joint pain in women taking aromatase inhibitors. These statements have not been evaluated by the U.S. Food and Drug Administration (FDA).
- Peyrol J, Riva C, Amiot MJ. Hydroxytyrosol in the prevention of the metabolic syndrome and related disorders. Nutrients. 2017;9(3).
- Esatbeyoglu T, Huebbe P, Ernst IM, Chin D, Wagner AE, Rimbach G. Curcumin--from molecule to biological function. Angew Chem Int Ed Engl.2012;51(22):5308-5332.
- Curcumin C3 Complex®-a versatile phytonutrient superior and safe choice. Curcumin C3 Complex® website. http://www.curcuminoids.com/index.php/introduction. Accessed May 26, 2017.
- U.S. Department of Health and Human Services, National Institutes of Health. Omega-3 fatty acids. National Center for Complementary and Integrative Health website. Available at: https://nccih.nih.gov/health/omega3. Updated July 12, 2016. Accessed April 10, 2017.
- About omega-3 and fish oil. Omega-3 website. http://www.omega-3.se/en/fishoil.html. Accessed April 10, 2017.
- Harper CR, Jacobson TA. Beyond the Mediterranean diet: the role of omega-3 fatty acids in the prevention of coronary heart disease. Prev Cardiol.2003;6(3):136-146.
- Omega-3 fatty acids. University of Maryland Medical Center website. http://www.umm.edu/Health/Medical/AltMed/Supplement/Omega-3-fatty-acid. Updated August 5, 2015. Accessed April 10, 2017.
- Swanson D, Block R, Mousa SA. Omega-3 fatty acids EPA and DHA: health benefits throughout life. Adv Nutr.2012;3(1):1-7.
- Fabian CJ, Kimler BF, Hursting SD. Omega-3 fatty acids for breast cancer prevention and survivorship. Breast Cancer Res.2015;17:62.
- Interim summary of conclusions and dietary recommendations on total fat & fatty acids. World Health Organization website. http://www.who.int/nutrition/topics/FFA_summary_rec_conclusion.pdf?ua=1. Published 2008. Accessed June 20, 2017.
- Report of the Joint FAO/WHO expert consultation on the risks and benefits of fish consumption. Rome, 25-29 January 2010. Food and Agriculture Organization of the United Nations website. http://www.fao.org/docrep/014/ba0136e/ba0136e00.pdf. Accessed July 11, 2017.
- Kris-Etherton PM, Harris WS, Appel LJ, American Heart Association Nutrition Committee. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation.2002;106(21):2747-2757.
- Siscovick DS, Barringer TA, Fretts AM, et al. Omega-3 polyunsaturated fatty acid (fish oil) supplementation and the prevention of clinical cardiovascular disease: a science advisory from the American Heart Association. Circulation. 2017;135(15):e867-e884.
- 2015-2020 Dietary Guidelines for Americans. 8th edition. U.S. Department of Health and Human Services and U.S. Department of Agriculture. Office of Disease Prevention and Health Promotion website. https://health.gov/dietaryguidelines/2015/resources/2015-2020_Dietary_Guidelines.pdf. Published December 2015. Accessed July 11, 2017.